It is tough to walk into an interview and not catalog the substance of your experience - the concrete things you've done.  You're proud of them and want to share the blood, sweat and tears that they represent. 

However, unless your target company wants you to replicate a specific experience, what you've done is largely irrelevant for the task at hand.  This is especially true of folks with higher degrees and those looking to change fields.

Your Goal:

Get the interviewer to check "hire" next to your name.

In other words, convince the interviewer that you represent a low downside risk (you won't reflect badly on them if they recommend you) and that she would like to work with you following a successful interview.

How to Get to "Hire":

1. Know your needs

2. Know what the position requires (and the company culture, more generally)

3. Match them together with each and every step of the interview

When to Share the Meat of Your Work:

Use it as the basis for concrete examples of your proficiency with relevant skills and how you face and overcome challenges.  A prepared candidate can readily pair glowing work experience examples with classic interview questions, such as:

Can you describe an occasion when you were in conflict with a coworker?  How did you resolve it?

or

What is your leadership philosophy?

Hiding behind the comforting wall of past achievements wastes the precious moments that you have to present yourself.  Take full advantage of the opportunity by sticking to what's relevant for the task at hand.